Product InformationPlavix Tablet (Clopidogrel) keeps blood platelets slippery and discourages formation of clots, thereby improving blood flow to your heart, brain, and body. Plavix Tablet (Clopidogrel) is prescribed to reduce the risk of heart attack, stroke, and serious circulation problems in people with hardening of the arteries or unstable angina (dangerous chest pain), and in people who've already suffered a heart attack or stroke. Because Plavix Tablet (Clopidogrel) slows clotting, it will take longer than usual to stop bleeding. Be sure to report any unusual bleeding to your doctor immediately, and tell any doctor or dentist planning a procedure that you have been taking Plavix Tablet (Clopidogrel). You should discontinue the Plavix Tablet (Clopidogrel) 5 days before any kind of surgery.
Plavix Tablet (Clopidogrel) can be taken with or without food.
PLAVIX SIDE EFFECTS:
Plavix Tablet (Clopidogrel) Side effects cannot be anticipated. If any Plavix side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Plavix Tablet (Clopidogrel).
More common Plavix side effects may include:
Abdominal pain, back pain, bronchitis, bruising and bleeding under the skin, chest pain, coughing, depression, diarrhea, difficulty breathing, dizziness, fatigue, fluid retention and swelling, flu symptoms, headache, high blood pressure, high cholesterol, indigestion, inflammation of the nasal passages, itching, joint pain, nausea, pain, purple discoloration of skin, rash, upper respiratory tract infection, urinary tract infection
Less common Plavix side effects may include:
Anemia, anxiety, arthritis, cataracts, constipation, fainting, fever, gout, heart problems, hernia, increased heart rate, insomnia, irregular heartbeat, joint disease, leg cramps, loss of sensitivity to touch, nosebleed, pinkeye, pneumonia, skin problems, stomach and intestinal bleeding, skin tingling, sinus inflammation, vomiting, weakness
Rare Plavix side effects may include:
Allergic reactions including swelling of the face and throat and difficulty breathing, bleeding in the eyes, confusion, decreased circulation in the skin, decreased white blood cell counts, excessive menstrual flow, fatal bleeding, hallucinations, kidney problems, liver problems, skin erruptions, stomach ulcers, taste disorders, wheezing, widespread internal bleeding.
Do not take Plavix Tablet (Clopidogrel) if you have a bleeding stomach ulcer or bleeding in the area around the brain. Also avoid Plavix Tablet (Clopidogrel) if it gives you an allergic reaction.
If you've ever had a stomach ulcer or bleeding in the digestive tract, make sure the doctor is aware of it; Plavix Tablet (Clopidogrel) should be used with caution. Plavix Tablet (Clopidogrel) should also be used carefully if you suffer from problems inside the eyes, have bleeding problems due to severe liver disease, or expect to be at risk of bleeding from any other cause.
In extremely rare cases (about 4 in a million), a dangerous bleeding problem called thrombotic thrombocytopenic purpura has been known to develop in patients taking Plavix Tablet (Clopidogrel). Signs include fever and bleeding under the skin. Call your doctor immediately if you develop these symptoms.
Plavix Tablet (Clopidogrel) increases the clot-fighting effect of aspirin. The two drugs are often taken together, and combined treatment has lasted for up to one year.
If Plavix Tablet (Clopidogrel) is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Ask your doctor before starting any new drug; and be doubly careful before combining Plavix Tablet (Clopidogrel) with the following:
Nonsteroidal anti-inflammatory drugs such as Advil, Aleve, Motrin, and Naprosyn
Potential symptoms of Plavix Tablet (Clopidogrel) overdose may include:
Difficulty breathing, exhaustion, stomach or intestinal bleeding, vomiting.
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Plavix, a Drug consisting of Clopidogrel Hydrogen Sulphate compound, and comes in the category of drugs called Antiplatelet medicines. Plavix is used for the prevention of blood clots in the blood. Plavix/Clopidogrel is manufactured jointly by Bristol-Myers Squibb and Sanofi Pharmaceuticals.
The major role of Plavix/Clopidogrel is to help the body so that no blood clots are formed. As blood clot is one of the most common reason of heart attack, heart failure and other cardiovascular diseases, hence, Plavix helps in the prevention of these blood clots. Plavix is used for the treatment of following problems:
- Reduction of further heart attacks: If a person had a heart attack in the past, which may have occurred due to the presence of blood clots in the blood, it becomes necessary that these blood clots are reduced. If the blood continues to form the clots, it may lead to further heart attacks, which is life threatening, and may lead to death.
- Reduction of further strokes: High blood pressure and high cholesterol could be the reasons for having a stroke or other heart problems, but they are generally supported by blood clots in the blood, which deteriorates the condition. Due to all these problems the person is unable to breath properly, feels shortness of breath, and these become very serious problems if not treated well in time.
A blood clot that forms inside the blood vessels is known as a thrombosis and can be dangerous, as it can cause a blockage that cuts off the blood supply to an organ. A blockage in the arteries supplying blood to the heart or brain can cause a heart attack or stroke. Blood clots and blockages mainly result from a build up of atherosclerosis on the inside of blood vessels, which is the build up of cholesterol and fat cells that narrows the blood vessels. This makes it more difficult for blood to flow through the vessels, and increases the likelihood of clots forming in the vessels. These events are known as atherothrombotic events.
Plavix works well in all the problems related to heart, where the heart stops working properly. It is then required that causes of these problems be rooted out, one amongst which is the blood clots. Plavix as an antiplatelet medicine helps in the reduction of these clots.
Plavix consists of a compound called clopidogrel that comes in the category of antiplatelet medicines. The function of these antiplatelet medicines, including Plavix is to help in thinning of blood. Plavix works by putting and end to the clubbing of platelets, which are blood cells. Also, Plavix prevents the bonding of a natural substance called ADP to its receptors on platelets.
The main cause of this clotting is the chemical called ADP, and Plavix stops this chemical from binding to platelets. Thus, it helps in the reduction of the formation of clots in the blood.. Clopidogrel is used to prevent blood clots forming within blood vessels, and therefore reduce the risk of further atherothrombotic events in these groups of people.
Hence, Plavix/Clopidogrel helps in further heart attacks and heart strokes by reducing the amount of blood clots.
Plavix/Clopidogrel must not be taken without the advice and consultation of a medical practitioner. A doctor can only identify the suitability of Plavix by well diagnosing all the related factors. There may be several areas that have to be looked into before taking Plavix/Clopidogrel.
As a general note, the dosage of Plavix/Clopidogrel depends from person to person, and one must consult his/her doctor before taking Plavix. However, the normal dosage of Plavix is 75mg per day. The dose of Plavix/Clopidogrel may need to be increased. Your doctor will advise whether the dose is to be taken a single dose or as two separate doses.
There is no specific time duration for which Plavix/Clopidogrel should be taken, as Plavix only helps in reducing the problem, rather it is a prevention, and does not cure the problem completely. As per the advice of a medical practitioner, Plavix/Clopidogrel may be taken for as long as required.
- Rashes / Itching
- Decrease in the amount of platelets
- Unusual tiredness or weakness, fatigue
- Dry mouth or throat
- Taste disturbances or loss of taste
- Confusion or nervousness
- Stomach pain
Note: The intensity of the above is generally mild to moderate.
- If one is allergic to Plavix/Clopidogrel or any other drug.
- If one has a problem of active bleeding called Hemorrhage, Plavix must not be used.
- Plavix must not be used after few days of heart attack or a stroke. There should be a gap of 1 week or more before Plavix can be taken.
- If one has a problem with Kidney or Liver, Plavix must be taken under doctor's guidance.
- It is not advisable to take Plavix by females who are breast feeding or are pregnant.
Plavix/Clopidogrel should be kept in the box until it is time to take them. If Plavix is taken out of the box they may not be good for use. And Plavix should be kept in a cool dry place where the temperature stays below 25°C. Plavix/Clopidogrel must not be kept on a windowsill or in the car on hot days. Keep Plavix/Clopidogrel where children cannot reach it.
- Bristol-Myers Squibb
- Boehringer Ingelheim
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