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Sandostatin (octreotide)

Sandostatin (octreotide)

Manufactured by: Novartis

This product requires a valid prescription

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Name Strength   Quantity Price  
 Brand  0.1mg/ml 5 x 1ml Ampules $119.99  Buy

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Sandostatin LAR® Depot (octreotide acetate for injectable suspension) is indicated for long-term maintenance therapy in acromegalic patients for whom medical treatment is appropriate and who have been shown to respond to and can tolerate Sandostatinsup® (octreotide acetate) Injection. The goal of treatment in acromegaly is to reduce GH and IGF-1 levels to normal. Sandostatin LAR® Depot can be used in patients who have had an inadequate response to surgery or in those for whom surgical resection is not an option. It may also be used in patients who have received radiation and have had an inadequate therapeutic response (See CLINICAL TRIALS and DOSAGE AND ADMINISTRATION

Carcinoid Tumors

Sandostatin LAR® Depot is indicated for long-term treatment of the severe diarrhea and flushing episodes associated with metastatic carcinoid tumors in patients in whom initial treatment with Sandostatin® Injection has been shown to be effective and tolerated.

Vasoactive Intestinal Peptide Tumors (VIPomas)

Sandostatin LAR® Depot is indicated for long-term treatment of the profuse watery diarrhea associated with VIP-secreting tumors in patients in whom initial treatment with Sandostatin® Injection has been shown to be effective and tolerated. In patients with acromegaly, carcinoid syndrome and VIPomas, the effect of Sandostatin® Injection and Sandostatin LAR® Depot on tumor size, rate of growth and development of metastases, has not been determined.


 

 

Drug Overview

Sandostatin is belongs to the family of hormone drugs also known as a synthetic (man-made) protein that is similar to the naturally-occurring hormone called somatostatin and commonly used for the treatment and prevention of the symptoms of Acromegaly and Hormone producing tumours. Sandostatin works by preventing the release of other hormones found in the body, including growth hormone and insulin.

Sandostatin is also used for the relief of symptoms caused by tumours of the gut, liver and pancreas (gastroenteropancreatic). Sandostatin is also used to reduce flushing and watery diarrhea caused by metastatic cancerous tumors (carcinoid syndrome) or tumors called vasoactive intestinal peptide tumors (VIPomas).

Sandostatin always takes under doctor’s guidance. You continue to take it for as long as your doctor prescribes it, even if you do not feel an immediate benefit. The dose of Sandostatin will be different for different patients; it is usually taken as directed by your health care professional. Sandostatin is also available in generic form known as Octreotide. Sandostatin may also be used for other conditions as determined by your doctor. Sandostatin is being manufactured by Novartis Pharmaceuticals Canada Inc. and is available in 50mcg/ml, 100mcg/ml and 200mcg/ml Injection.

Effects - How it works in the body

Sandostatin is belongs to the family of hormone drugs also known as a synthetic (man-made) protein that is similar to the naturally-occurring hormone called somatostatin and commonly used for the treatment and prevention of the symptoms of Acromegaly and Hormone producing tumours. Sandostatin works by preventing the release of other hormones found in the body, including growth hormone and insulin. Somatostatin is produced in various parts of the body such as the brain, gut and pancreas. Somatostatin is used for the relief of symptoms of tumours in the body that produce excessive amounts of hormones, such as in acromegaly. A tumour in the part of the brain known as the pituitary gland causes acromegaly and it is this tumour that produces excessive amounts of growth hormone. Therefore Somatostatin is used for the treatment of the symptoms of acromegaly by decreasing levels of growth hormone in the body, but it is not however used to treat the actual tumour.

Side Effects

Possible side effects that occurs during the uses of Sandostatin:

  • Allergic reactions
  • Chest pain
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Fatigue
  • Nausea
  • Diarrhea
  • Difficulty breathing
  • Headache
  • Palpitations
  • Tremor
  • Vomiting
  • Agitation
  • Anxiety
  • Blurred vision
  • Bone pain
  • Burning eyes
  • Confusion
  • Constipation
  • Depression
  • Irregular heartbeat
  • Heart attack
  • Hives
  • Increased blood pressure
  • Increased urination
  • Indigestion
  • Insomnia
  • Irritability
  • Itching
  • Menstruation disorder
  • Muscle cramp
  • Nasal irritation
  • Sinus problems
  • Stomach bloating
  • Stroke
  • Throat irritation
  • Wheezing
  • Vertigo
  • Unusual tiredness or weakness
  • Weight gain
  • Yellow eyes or skin

Interactions

Although certain medicines should not be used together at all, so its your responsibilities that tell your doctor or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also you tell your doctor or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or addicted to illegal drugs. These may affect the working mechanism of Sandostatin. In these cases, your doctor may change the dose or teach precautions may be necessary. Therefore when you are taking Sandostatin, it is most important that your doctor or health care professional know if you are taking any other drugs or alcohol.

  • Cisapride
  • Cyclosporine
  • Medicines which used for the treatment of diabetes or insulin and other drugs as:
  • Glipizide or Glucotrol
  • Glyburide or Diabeta, Micronase
  • Tolbutamide or Orinase
  • Metformin or Glucophage
  • Pioglitazone or Actos
  • Rosiglitazone or Avandia
  • Medicines which used for the treatment of heart disease or hypertension
  • Diuretics or water pills

Counterindications

You shouldn’t use this drug without consultation of doctor if you have an allergy to Sandostatin or any other ingredients of this medicine.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the problem of decreased liver function, Asthma or other lung disease.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the problem of Kidney disease.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the problem of Heart disease.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the problems of Diabetes mellitus or sugar diabetes.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the problems of gallbladder disease.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the thyroid problems.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the problem of pancreatitis.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to the problem of paralysis of the stomach wall (gastroparesis).

You shouldn’t use Sandostatin without consultation of doctor if you are pregnant or plan to be pregnant.

You shouldn’t use Sandostatin without consultation of doctor if you are suffering to breastfeeding.

Similar drugs of Sandostatin

  • Sandostatin LAR Depot
  • Octreotide
  • Octreotide acetate
  • Bromocriptine
  • Somatuline
  • Somavert

Major drug Manufacturers

  • Novartis Pharmaceuticals Canada Inc.
  • Sandoz Pharmaceuticals Canada Inc.
  • PolyPeptide Laboratories
  • Sartorius India Pvt. Ltd.
  • Bedford Laboratories
  • Mylan Laboratories
  • Sigma Pharmaceuticals
  • Ipsen Pharmaceuticals
  • Boehringer Ingelheim Pharmaceuticals
  • Pfizer Pharmaceuticals Canada Inc

From where can one get Sandostatin?

Anyone can buy Sandostatin from Online Canadian Pharmacy, which is available at a discounted price, 50% off, in Canada, and the best way to get Sandostatin is by logging on to http://www.abconlinepharmacy.com for online orders. This pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order.

Why to buy Sandostatin drug from Canada?

It is cheaper to buy Sandostatin from Online Canadian Pharmacy, because Canadian government regulates the prices of Sandostatin and also because of the very common reason of exchange rate. Since, the Canadian dollar is cheaper as compared to the US Dollars, so one can buy more Sandostatin from Canada, thereby saving a lot of money.

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