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Rapamune (Sirolimus Tablets)

Rapamune (Sirolimus Tablets)

Manufactured by: Wyeth Ayerst Pharmaceuticals

This product requires a valid prescription

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Name Strength   Quantity Price  
 Brand  1mg 100 Tabs $899.99  Buy

      All prices in USD


Rapamune is an anti-rejection drug for patients who have had an kidney transplant. While taking RAPAMUNE and cyclosporine, you will need to have periodic blood tests to check your blood cholesterol and triglycerides. Your doctor may recommend treatment if your blood cholesterol or triglycerides become too high. In patients taking RAPAMUNE with cyclosporine, increased blood creatinine levels have been observed, indicating a decrease in kidney function. Because of this, your doctor will be checking your blood creatinine level and may adjust your medications. You should also be aware that many prescription and nonprescription drugs can affect your kidney. Always check with your doctor before taking any new medications. Women of childbearing potential should use effective birth control prior to initiation of RAPAMUNE therapy, during RAPAMUNE therapy, and for 12 weeks after RAPAMUNE therapy has been stopped.

Sirolimus (sir-OH-li-mus) Given after a kidney transplant to keep your body from rejecting the new kidney. Usually given in combination with other medicines, including steroids.

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
If you are also taking cyclosporine (Sandimmune®, Neoral®), take it at least 4 hours before taking sirolimus.
There are many other medicines that can interact with sirolimus. Make sure your doctor knows about ALL other medicines you are using while you are taking sirolimus.
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
Talk to your doctor before getting flu shots or other vaccines while you are receiving sirolimus. Vaccines may not work as well while you are using this medicine.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant, and keep using it for at least 12 weeks after you stop taking sirolimus. If you think you have become pregnant while using the medicine, tell your doctor right away.
Make sure your doctor knows if you are breastfeeding, or if you have a history of skin cancer, high cholesterol or triglyceride levels in your blood, cytomegalovirus (CMV), or liver disease.
This medicine may increase your chances of getting an infection or of developing certain types of cancer, especially skin cancer. Avoid people who are sick or have infections.
Limit your exposure to sunlight. Always wear protective clothing and sunscreen with a high SPF number. Avoid sunlamps and tanning beds.
Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

SIROLIMUS (Oral) (Tablet) Side Effects
Call your doctor right away if you notice any of these side effects:
Fast or irregular heartbeat
Fever, chills, sore throat
Trouble breathing
Unusual bleeding or bruising, pale skin
Unusual weakness or tiredness If you notice these less serious side effects, talk with your doctor:
Diarrhea
Joint pain
Rash or acne
Shakiness or tremors


 

 

Drug Overview

Rapamune is belongs to the family of drugs known as an Immunosuppressant medication and commonly used for the treatment and improvement of lower the body's natural immunity in patients who receive kidney transplants. When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Rapamune works by preventing the white blood cells from getting rid of the transplanted organ.

Rapamune is a medication used to decrease the immune system's response to a transplanted organ. Rapamune helps to reduce immune responses and prevent organ rejection in patients who have received a kidney or other organ transplant.

Rapamune always takes under doctor’s guidance. You continue to take it for as long as your doctor prescribes it, even if you do not feel an immediate benefit. The dose of Rapamune will be different for different patients; it is usually taken once a day in the morning or otherwise as directed by your health care professional. Anybody should take the recommended oral dosage of Rapamune with food and a full glass of water. Rapamune is also available in generic form Sirolimus. Rapamune may also be used for other conditions as determined by your doctor. Rapamune is being manufactured by Wyeth Ayerst Pharmaceuticals and is available in 1mg Tablets.

Effects - How it works in the body

Rapamune is belongs to the family of drugs known as an Immunosuppressant medication and commonly used for the treatment and improvement of lower the body's natural immunity in patients who receive kidney transplants. When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Rapamune works by preventing the white blood cells from getting rid of the transplanted organ.

Side Effects

Possible side effects that occurs during the uses of Rapamune:

  • Allergic reactions
  • Abdominal cramps or pain
  • Accumulation of pus
  • Anxiousness
  • Backache
  • Bleeding from gums or nose
  • Blindness
  • Bloody or cloudy urine
  • Blue lips and fingernails
  • Blurred vision
  • Body aches or pain
  • Bone pain
  • Bruising
  • Burning while urinating
  • Burning, dry, or itching eyes
  • Burning or stinging of skin
  • Pain in the hands, arms, feet, or legs
  • Change in mental status
  • Changes in skin color
  • Chills
  • Cold hands and feet
  • Confusion
  • Convulsions or seizures
  • Cough
  • Coughing up blood
  • Dark or bloody urine
  • Decreased urge to urinate
  • Decreased vision
  • Difficulty in breathing or swallowing
  • Difficulty speaking
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Ear congestion
  • Earache
  • Excessive tearing
  • Eye pain
  • Facial hair growth in females
  • Fainting
  • Irregular heartbeat
  • Fatigue
  • Fever
  • Increased menstrual flow or vaginal bleeding
  • Irregular breathing
  • Irritability
  • Lack or loss of appetite
  • Loss of consciousness
  • Loss of sexual ability
  • Lower back or side pain
  • Lump in abdomen
  • Menstrual irregularities
  • Mood changes
  • Muscle pain
  • Nasal congestion
  • Nausea or vomiting
  • Pain in chest, groin, or legs
  • Pale skin
  • Paralysis
  • Pus in urine
  • Ringing in the ears
  • Runny nose
  • Constipation
  • Headache
  • Sneezing
  • Stomach pain or upset
  • Stomachache
  • Tightness in chest
  • Tiredness
  • Tremor
  • Ulcers on lips or in mouth
  • Unusual tiredness or weakness
  • Weight gain
  • Yellow eyes or skin

Interactions

Although certain medicines should not be used together at all, so its your responsibilities that tell your doctor or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also you tell your doctor or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or addicted to illegal drugs. These may affect the working mechanism of Rapamune. In these cases, your doctor may change the dose or teach precautions may be necessary. Therefore when you are taking Rapamune, it is most important that your doctor or health care professional know if you are taking any of the following or other drugs:

  • Amiodarone
  • Bosentan
  • Carbamazepine
  • Cimetidine
  • Cisapride
  • Clarithromycin
  • Cyclosporine
  • Diltiazem
  • Erythromycin
  • Fluoxetine
  • Fluvoxamine
  • Imatinib
  • Medicines for fungal infections or antifungal medicines
  • Medicines for HIV infection including protease inhibitors as Delavirdine, Efavirenz
  • Metoclopramide
  • Micafungin
  • Mifepristone
  • Nefazodone
  • Nicardipine
  • Oxcarbazepine
  • Phenobarbital
  • Phenytoin
  • Rifabutin
  • Rifampin
  • Rifapentine
  • St. John's wort
  • Telithromycin
  • Vaccines
  • Verapamil
  • Aspirin
  • Acetaminophen
  • Ibuprofen
  • Ketoprofen
  • Naproxen

Counterindications

You shouldn’t use this drug without consultation of doctor if you have an allergy to Rapamune or any other ingredients of this medicine.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of decreased liver function, Asthma or other lung disease.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of Liver transplantation or Lung transplantation.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of Kidney disease.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of Heart disease or Blood disease.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of high cholesterol or triglycerides.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of an active infection.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of Cancer.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of Chickenpox.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to the problem of Herpes zoster (shingles).

You shouldn’t use Rapamune without consultation of doctor if you are pregnant or plan to be pregnant.

You shouldn’t use Rapamune without consultation of doctor if you are suffering to breastfeeding.

Similar drugs of Rapamune

  • Sirolimus
  • Neoral
  • Ciclosporin
  • Sandimmune
  • Tacrolimus
  • Prograf
  • Mycophenolate mofetil
  • SangCya
  • Gengraf
  • Consupren (Mexico)

Major drug Manufacturers

  • Wyeth Ayerst Pharmaceuticals
  • Novartis Pharmaceutical
  • CIPLA Pharmaceutical
  • Sandoz Pharmaceutical
  • Fujisawa Pharmaceutical Company Ltd.
  • Roche Pharmaceutical
  • Aventis Pharmaceutical Products
  • IVAX Pharmaceuticals

From where can one get Rapamune?

Anyone can buy Rapamune from Online Canadian Pharmacy, which is available at a discounted price, 50% off, in Canada, and the best way to get Rapamune is by logging on to http://www.abconlinepharmacy.com for online orders. This pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order.

Why to buy Rapamune drug from Canada?

It is cheaper to buy Rapamune from Online Canadian Pharmacy, because Canadian government regulates the prices of Rapamune and also because of the very common reason of exchange rate. Since, the Canadian dollar is cheaper as compared to the US Dollars, so one can buy more Rapamune from Canada, thereby saving a lot of money.

Buy Rapamune at Canada Pharmacy Prescription Drug Store