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Plavix was tested in a clinical environment with over 17,500 patients, including 9,000 patients treated for 1 year or more. Overall tolerability of Plavix was similar to aspirin, with an approximately equal incidence of patients withdrawing from treatment due to adverse reactions. Some of the more commone side effects of Plavix were:

• Minor bleeding
• Chest pain
• Pupura/Bruise
• Upper respiratory tract infection
• Headache
• Accidental/Inflicted injury
• Rash
• Coughing
• Pruritus

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