Coumadin

Coumadin is called an anticoagulant because it works against the formation of blood clots that could be harmful to you. Although Coumadin is sometimes called a "blood-thinner," it works in the liver by blocking the use of vitamin K to decrease the production of natural blood components called clotting factors. In many cases, Coumadin is used as a preventative treatment to reduce the chance of forming a blood clot that could hurt you. Coumadin therapy is also used by people who have already experienced a serious blood clot.

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Coumadin Side Effects

Coumadin side effects do not happen oftern, however, if you experience any of the following serious side effects from warfarin, stop taking Coumadin and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • black, bloody, or tarry stools;
  • blood in urine or vomit;
  • coughing up blood;
  • bleeding gums or sores in the mouth;
  • decreased urine production;
  • yellowing of the skin or eyes;
  • severe dizziness or headache;
  • easy bleeding or bruising under the skin;
  • purple discoloration of the toes or fingers;
  • sudden leg or foot pain; or
  • unusually heavy menstrual periods.

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Coumadin Precautions

Never take a double dose of this medication. Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox), and others while taking warfarin, except under the direction of your doctor.

These medicines increase the risk of bleeding. Avoid sudden changes in your diet. Vitamin K decreases the effects of warfarin. Large amounts of vitamin K are found in foods such as liver, broccoli, brussels sprouts, and green leafy vegetables (e.g., spinach, Swiss chard, coriander, collards, cabbage). Do not change the amount of these foods in your diet without first talking to your doctor. It will be necessary to regularly monitor your therapy with a blood test called a "PT" or an "INR." These tests help to determine the amount of warfarin that you need to take. Contact your doctor if you experience any unusual bruises or heavily bleeding wounds, diarrhea, infection, or fever during treatment with warfarin.

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Coumadin Manufacturer

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