Protonix (pantoprazole)
Protonix belongs to the family of medications called proton pump inhibitors (PPIs). Protonix slows or prevents the production of acid within the stomach. Protonix is used for the treatment of conditions where reduction in acid secretion is required for proper healing, including stomach and intestinal ulcers (gastric and duodenal ulcers), heartburn, and gastroesophageal reflux disease (GERD). Protonix is also used in combination with antibiotics for the treatment and eradication of H. pylori bacteria (the cause of most duodenal ulcers).
Pantoprazole
Pantoprazole sodium sesquihydrate is a white to off- white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium sesquihydrate is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n- hexane. The stability of the compound in aqueous solution is pH- dependent. The rate of degradation increases with decreasing pH. At ambient temperature, the degradation half-life is approximately 2.8 hours at pH 5.0 and approximately 220 hours at pH 7.8.
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Canadian Protonix
Protonix is available in strengths of 20 mg and 40 mg.
20 mg: Each enteric-coated, yellow, oval, tablet, marked "P20" on one side, contains pantoprazole 20 mg. Nonmedicinal ingredients: anhydrous sodium carbonate, calcium stearate, crospovidone, ferric oxide, mannitol, methylhydroxypropyl cellulose, poly(ethylacrylate, methacrylic acid), polysorbate 80, polyvidone, propylene glycol, sodium lauryl sulfate, titanium dioxide, and triethyl citrate.
40 mg: Each enteric-coated, yellow, oval, tablet, marked "P40" on one side, contains: pantoprazole 40 mg. Nonmedicinal ingredients: anhydrous sodium carbonate, calcium stearate, crospovidone, ferric oxide, mannitol, methylhydroxypropyl cellulose, poly(ethylacrylate, methacrylic acid), polysorbate 80, polyvidone, propylene glycol, sodium lauryl sulfate, titanium dioxide, and triethyl citrate.
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Protonix Side Effects
Protonix (pantoprazole) is usually very well tolerated. The most common side effects of Protonix were:
- headache
- aching, fullness, or tension in sinuses
- anxiety
- back pain
- belching
- blurred vision
- chills
- confusion
- constipation
- cough
- difficulty moving
- dizziness
- drooling
- feeling of constant movement of self or surroundings
- flatulence
Protonix Precautions
Pantoprazole sodium should not be taken by anyone with an allergy to pantoprazole or to any of the ingredients of the medication.
Protonix Manufacturer
No information is available about the manufacturer of Protonix at this time.
