Premarin (estrogen)
Premarin is a estrogen replacement therapy medication. Estrogen is the female hormone that is produced by the ovaries. Once a woman reach menopause, the ovaries produce less estrogen and symptoms of menopause can occur. Premarin is an estrogen replacement hormone used for the management of menopausal symptoms such as abnormal uterine bleeding, hot flashes, sweating, and chills. Premarin has also been used by women to prevent and treat osteoporosis. Premarin may be used as palliative treatment for certain men with inoperable progressive prostate cancer.
Conjugated Estrogens
Conjugated estrogens is a mixture of estrogens obtained exclusively from natural sources, occurring as the sodium salts of water-soluble estrogen sulfates blended to represent the average composition of material derived from pregnant mares' urine. Cojugated estrogens contain estrone, equilin, and 18 alpha-dihydroequilin, together with smaller amounts of 17 alpha-estradiol, equilein, and 17 alpha-dihydroequilenin as salts of their sulfate esters.
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Canadian Premarin
Tablets of Premarin are available for oral administration in 0.3 mg, 0.625 mg, 0.9 mg, 1.25 mg, and 2.5 mg strengths of conjugated estrogens.
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Premarin Side Effects
Premarin (estrogen) is usually very well tolerated. The most common side effects of Premarin were:
- bloating of stomach
- cramps of lower stomach
- loss of appetite
- nausea
- diarrhea (mild)
- dizziness (mild)
- headaches (mild)
- migraine headaches
- problems with wearing contact lenses
- unusual decrease in sexual desire (in males)
- unusual increase in sexual desire (in females)
- vomiting (usually with high doses)
Premarin Precautions
Premarin (estrogen) should not be used by anyone who:
- has a history of known or suspected estrogen-dependent tumours such as breast or uterine cancer
- has undiagnosed abnormal vaginal bleeding
- is known or suspected to be pregnant
- has active liver disease or dysfunction, especially of the obstructive type
- has active thrombophlebitis, thrombosis, or thromboembolic disorders (blood clotting problems)
- has endometrial hyperplasia
- is allergic to any of the ingredients of the medication
Premarin Manufacturer
No information is available about the manufacturer of Premarin at this time.
