Lamisil (terbinafine)
Lamisil (terbinafine) belongs to a class of medications called antifungals. Lamisil is used for the treatment of certain types of fungal infections of the skin and nails. Lamasi tablets should be taken once daily for 6 weeks by patients with fingernail onychomycosis. Lamisil, one 250 mg tablet, should be taken once daily for 12 weeks by patients with toenail onychomycosis. The optimal clinical effects is seen some months after mycological cure and cessation of treatment. This is related to the period required for outgrowth of healthy nails.
Terbinafine
Lamisil (terbinafine hydrochloride tablets) Tablets contain the synthetic allylamine antifungal compound terbinafine hydrochloride. Terbinafine hydrochloride is a white to off- white fine crystalline powder. It is freely soluble in methanol and methylene chloride, soluble in ethanol, and slightly soluble in water. Terbinafine is well absorbed soon after administration (> 70%) and the bioavailability of Lamasil tablets as a result of first-pass metabolism is approximately 40%.
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Canadian Lamisil
Lamisil is available as tablets, cream, and spray.
Tablets: Each round, whitish-yellow, uncoated tablet, scored on one side and embossed "Lamisil 250", contains terbinafine 250 mg. Nonmedicinal ingredients: cellulose microcrystalline, magnesium stearate, methylhydroxypropyl cellulose, silica, colloidal anhydrous, and sodium carboxymethyl starch.
Cream: Each gram of white, smooth, glossy cream contains terbinafine 10 mg. Nonmedicinal ingredients: benzyl alcohol, cetyl alcohol, cetyl palmitate, isopropyl myristate, polysorbate 60, purified water, sodium hydroxide, sorbitan monostearate, and stearyl alcohol.
Spray: Each gram of clear solution contains terbinafine 10 mg. Nonmedicinal ingredients: cetomacrogol 1,000, ethanol, propylene glycol, and water. Alcohol: 28.8% v/v.
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Lamisil Side Effects
Lamisil (terbinafine) is usually very well tolerated. The most common side effects of Lamisil were:
- diarrhea
- nausea and vomiting
- stomach pain (mild)
- change of taste or loss of taste
- dryness
- redness
- itching
- burning
- peeling
- rash
- stinging
- tingling
- other signs of skin irritation not present before use of this medication
Lamisil Precautions
Rare cases of symptomatic hepatobiliary dysfunction including cholestatic hepatitis have been reported. Treatment with Lamisil (terbinafine hydrochloride tablets) Tablets should be discontinued if hepatobiliary dysfunction develops
Lamisil Manufacturer
No information is available about the manufacturer of Lamisil at this time.
