Product Information
Enbrel (Etanercept) is a treatment used to reduce the signs and symptoms of moderate-to-severe rheumatoid arthritis in people 4 years of age and over. Enbrel (Etanercept) is used to slow down the progression of joint damage caused by psoriatic arthritis and reduce the signs and symptoms of this condition in adultsreduce the signs and symptoms of active ankylosing spondylitis and to treat adults with chronic moderate-to-severe plaque psoriasis who are eligible for oral treatment or phototherapy.
Enbrel (Etanercept) works by "turning down" parts of the body's immune system that are believed to be responsible for causing rheumatoid arthritis symptoms. The benefits of using Enbrel (Etanercept) may be seen as early as one week after the start of treatment, with the full effect usually achieved by three months. The symptoms of the condition being treated with Enbrel (Etanercept) usually return within one month after Enbrel (Etanercept) is stopped.
Enbrel (Etanercept) should not be used by anyone who:
is suffering from, or who is at risk for, sepsis syndrome
has a serious infection
has an active infection that is not yet being treated (regardless of whether the infection is chronic or located only in one area of the body)
is allergic to etanercept or any of the ingredients of the medication
is taking anakinra
To read Health Canada's advisory regarding Enbrel, Please visit:
http://www.hc-sc.gc.ca/dhp-mps/medeff/advisories-avis/public/2006/anti-tnf_therapy_pc-cp_e.html
- Drug Overview
- Effects - How it works in the body
- Side Effects
- Interactions
- Counterindications
- Similar drugs of Enbrel
- Major drug Manufacturers
- From where can one get Enbrel?
Enbrel is a monoclonal antibody belongs to the family of an inflammatory bowel disease therapy agent's also known as Antirheumatic (biologic response modifier) group medication and commonly used for the treatment and prevention or relieve of the symptoms of rheumatoid arthritis and psoriatic arthritis. Enbrel works by binding to and preventing the activity of a specific protein produced by the body known as tumor necrosis factor alpha (TNF alpha).
Enbrel is also used to treat rheumatoid arthritis and ankylosing spondylitis which is a type of arthritis that affects the joints in the spine. Enbrel is also used to treat psoriatic arthritis which is a type of arthritis that causes pain and swelling of the joints and patches of scaly skin on some areas of the body. Psoriatic arthritis is related to the skin condition, psoriasis. Sometimes Enbrel is also used to treat Reactive arthritis and Inflammatory bowel disease arthritis.
Enbrel always use under doctor's guidance. You continue to use it for as long as your doctor prescribes, even if you do not feel an immediate benefit. The dose of Enbrel will be different for different patients; it is usually taken once a day or otherwise as directed by your health care professional. Enbrel is available as generic name Etanercept Injection Vials and may also be used for other conditions as determined by your doctor. Enbrel is being manufactured by Immunex Corporation and is available in 25mg/vial injections.
Effects - How it works in the body
Enbrel is a monoclonal antibody belongs to the family of an inflammatory bowel disease therapy agent's also known as Antirheumatic (biologic response modifier) group medication and commonly used for the treatment and prevention or relieve of the symptoms of rheumatoid arthritis and psoriatic arthritis. Enbrel works by binding to and preventing the activity of a specific protein produced by the body known as tumor necrosis factor alpha (TNF alpha). TNF alpha is involved in producing inflammation. It controls the activity of other inflammatory chemicals. TNF alpha is found in the inflamed joints of people with rheumatoid arthritis and in the inflamed lining of the intestine of people with Crohn's disease. Preventing the action of TNF alpha prevents the inflammatory responses it causes. Enbrel also reduces the presence of other inflammatory markers.
Enbrel is used to reduce the signs and symptoms of rheumatoid arthritis and improve physical function of the joints. Enbrel is used in combination with Methotrexate to treat this disease when disease modifying antirheumatic drugs (DMARDs, eg sulfasalazine, methotrexate) has not been effective.
Possible side effects that occur during the uses of Enbrel:
- Allergic reactions
- Abdominal pain
- Cough
- Dizziness
- Fainting
- Headache
- Muscle pain
- Nasal congestion
- Nausea
- Runny nose
- Shortness of breath
- Sneezing
- Sore throat
- Tightness in chest
- Vomiting
- Back pain
- Bloody or cloudy urine
- Diarrhea
- Difficult or painful urination
- High blood pressure
- Low blood pressure
- Pain or tenderness around eyes and cheekbones
- Skin rash
- Bone or joint pain
- Constipation
- Infection
- Irregular or pounding heartbeat
- Pain in rectum
- Unusual bleeding or bruising
- Unusual tiredness or weakness
- Weight gain
- Yellow eyes or skin
Although certain medicines should not be used together at all, so its your responsibilities that tell your doctor or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also you tell your doctor or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or addicted to illegal drugs. These may affect the working mechanism of Enbrel. In these cases, your doctor may change the dose or teach precautions may be necessary. Therefore when you are taking Enbrel, it is most important that your doctor or health care professional know if you are taking any of the following or other drugs:
- Alcohol
- Anakinra
- Cyclophosphamide or Cytoxan
- Vaccines
- Kineret
- Immunosuppressive therapy
- Medicine which used to prevent your body from rejecting an organ transplant
You shouldn't use this drug without consultation of doctor if you have an allergy to Enbrel or any other ingredients of this medicine.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problem of liver disease.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problem of Kidney disease.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problem of Heart disease or Blood disorders.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problems of Diabetes mellitus or sugar diabetes.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problem of depressed immune function or immune disorders.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problems of multiple sclerosis.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problem of seizure disorder.
You shouldn't use Enbrel without consultation of doctor if you are suffering to the problem of Cancer disease.
You shouldn't use Enbrel without consultation of doctor if you are pregnant or plan to be pregnant.
You shouldn't use Enbrel without consultation of doctor if you are suffering to breastfeeding.
- Etanercept
- Remicade
- Infliximab
- Humira
- Adalimumab
- Immunex Corporation
- Schering-Plough Pharmaceuticals
- Abbott Laboratories Ltd.
- Celltech Pharmaceuticals
- UCB Pharmaceuticals
- Wyeth Pharmaceuticals
- Johnson & Johnson Pharmaceutical
From where can one get Enbrel?
Anyone can buy Enbrel from Online Pharmacy, which is available at a discounted price, 50% off, and the best way to get Enbrel is by logging on to http://www.abconlinepharmacy.com for online orders. This pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order.
